Dennemeyer Octimine

Cancer patents

Laura HorcajadaLaura Horcajada

Method of producing cancer stem cell

A method of producing a cancer stem cell comprising the step of in vitro cell fusion of a tumor cell and a blood cell (for example, blood cells including a hematopoietic stem cell and/or a precursor cell) and a method of producing a cancer-bearing model animal comprising the step of administering a mixture of the cancer stem cell obtained by the cell fusion of a tumor cell and a blood cell and the tumor cell to a non-human mammal.

Publication number: WO2006115243A1 | Search similar patents

Composition for prevention and treatment of colon adenomas

The present invention provides a composition capable of reducing the risk of colon adenoma formation. This composition will be useful for the prevention and treatment of colon cancer through the combination of the ingredients disclosed.

Publication number: WO2005112955A1 | Search similar patents

Incentive based health care insurance program

Apparatuses, systems, programs, and/or methods of administering an incentive health care insurance program are provided. In one aspect, the apparatuses, systems, programs, and/or methods comprise offering one or more incentives to a participant of a health care insurance program to complete a health risk assessment questionnaire or a biometric measurement analysis, and/or to provide a biosample for biomedical analysis; scoring, ranking, and/or grading the health risk assessment and/or the biometric parameters for one or more health risks; analyzing the biosample for one or more biomedical parameters; analyzing the scored, ranked, and/or graded health risk assessment questionnaire and/or the biometric parameters, and/or biomedical parameters and determining a Health Score to assess for presence or risk of disease; and optionally providing one or more additional incentives to the one or more participants to achieve, maintain, or improve their Health Score and/or an individual parameter of a Health Score.

Publication number: US2005228692A1 | Search similar patents

Cancer diagnosis device

The present invention provides a cancer diagnosis device which identifies low mass ions for diagnosing a specific cancer through biostatistical analysis with respect to low mass ions extracted from a biological sample, and can diagnose the specific cancer using the mass spectrum of the low mass ions. The present invention provides a discriminant which allows patient groups of colorectal cancer, breast cancer, and gastric cancer to be strongly discriminated from non-patient groups thereof, respectively. In other words, provided are a discriminant which shows an excellent and strong discrimination property with respect to a training set from which the discriminant is derived and a validation set independent thereon, and a cancer diagnosis device capable of diagnosing colorectal cancer, breast cancer, gastric cancer, and the like by identifying low mass ions constituting the same.

Publication number: WO2013103197A1 | Search similar patents

Method and apparatus for the diagnosis of colorectal cancer

A process is set forth in which cancer of the colon is assessed in a patient. The probabilities of developing cancer involves the initial step of extracting a set of sample body fluids from the patient. Fluids can be evaluated to determine certain marker constituents in the body fluids. Fluids which are extracted have some relationship to me development of cancer, precancer or tendency toward cancerous conditions. The body fluid markers are measured and other quantified. The marker data then is evaluated using a nonlinear technique exemplified through the use of a multiple input and multiple output neural network having a variable learning rate and training rate. The neural network is provided with data from other patients for the same or similar markers. Data from other patients who did and did not have cancer is used in the leaning of the neural network which thereby processes the data and provides a determination that the patient has a cancerous condition, precancer cells or a tendency towards cancer.This application is a divisional of application Ser. No. 07/989,647 filed Dec. 11, 1992, now abandoned.

Publication number: US5790761A | Search similar patents

Methods of diagnosing cancer, compositions, and methods of screening for cancer modulators

Described herein are methods that can be used for diagnosis and prognosis of breast and/or colorectal cancer. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate breast and/or colorectal cancer. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in breast and/or colorectal cancer are described.

Publication number: US6566502B1 | Search similar patents

Determination of cancer predisposition

Disclosed herein are systems and methods for using demethylation of genomic DNA for diagnosing, predicting, and/or monitoring the status or outcome of a neoplasm or a cancer in a subject.

Publication number: US2013210124A1 | Search similar patents

Method of treating or inhibiting colonic polyps and colorectal cancer

This invention provides a method of treating or inhibiting colonic polyps or treating or inhibiting colorectal cancer in a mammal in need thereof which comprises administering to said mammal an NSAID and an EFGR kinase inhibitor.

Publication number: US6432979B1 | Search similar patents

Method and apparatus for determining familial risk of disease

Personal and family health history information can be used to assess familial risk of disease. For example, information can be collected about the disease history of a person and the person's first- and second-degree relatives and then analyzed to determine the familial risk of common diseases such as coronary heart disease, stroke, type 2 diabetes, and colorectal, breast, and ovarian cancer. Assessed familial risk of disease can then be used by researchers to better estimate the contribution of personal history and family history to the etiology and natural history of a disease of interest, and by consumers and health professionals to determine recommendations for disease management, prevention and screening that are personalized and targeted to the familial risk. Other embodiments are also described and claimed.

Publication number: US2006173717A1 | Search similar patents

Incentive based health care insurance program

Apparatuses, systems, programs, and/or methods of administering an incentive health care insurance program are provided. In one aspect, the apparatuses, systems, programs, and/or methods comprise offering one or more incentives to a participant of a health care insurance program to complete a health risk assessment questionnaire or a biometric measurement analysis, and/or to provide a biosample for biomedical analysis; scoring, ranking, and/or grading the health risk assessment and/or the biometric parameters for one or more health risks; analyzing the biosample for one or more biomedical parameters; analyzing the scored, ranked, and/or graded health risk assessment questionnaire and/or the biometric parameters, and/or biomedical parameters and determining a Health Score to assess for presence or risk of disease; and optionally providing one or more additional incentives to the one or more participants to achieve, maintain, or improve their Health Score and/or an individual parameter of a Health Score.

Publication number: EP1738318A2 | Search similar patents

Macrophage-enhanced mri (memri)

Methods for assessing stage of cancer in a subject are provided, comprising administering a macrophage imaging agent to the subject, making a magnetic resonance image of regions of the subject's body at cancer risk, and using the image to assess macrophage density and displacement associated with any primary cancer or metastatic cancer in the subject, such density and displacement being indicative of neoplasia. The macrophage imaging agent may be an ultrasmall superparamagnetic iron oxide particle and in particular embodiments, the macrophage imaging agent has a blood half-life sufficient to permit microphage trapping throughout the regions at cancer risk. Additional embodiments provide methods for assessing efficacy of an anticancer treatment in a subject, methods for determining frequency of follow-up MEMRI evaluation in a subject, methods for determining metastatic potential of cancer foci in a subject, and methods for determining prognosis of cancer in a subject. Methods for directing site of biopsy in a subject by performing a whole body MEMRI evaluation of the subject to identify macrophage density at a tumor site of interest and assessing the macrophage density to identify the site of biopsy in the subject, macrophage density being an indicator of tumor growth are also provided, in addition to methods for providing individualized cancer treatment to a subject in need thereof using whole body MEMRI evaluation.

Publication number: WO2009006146A1 | Search similar patents

Method and apparatus for the diagnosis of colorectal cancer

A process is set forth in which cancer of the colon is assessed in a patient. The probabilities of developing cancer involves the initial step of extracting a set of sample body fluids from the patient. Fluids can be evaluated to determine certain marker constituents in the body fluids. Fluids which are extracted have some relationship to me development of cancer, precancer or tendency toward cancerous conditions. The body fluid markers are measured and other quantified. The marker data then is evaluated using a nonlinear technique exemplified through the use of a multiple input and multiple output neural network having a variable learning rate and training rate. The neural network is provided with data from other patients for the same or similar markers. Data from other patients who did and did not have cancer is used in the learning of the neural network which thereby processes the data and provides a determination that the patient has a cancerous condition, precancer cells or a tendency towards cancer.This is a Continuation Application of application Ser. No. 08/788,661 filed on Jan. 24, 1996, now U.S. Pat. No. 5,790,761.

Publication number: US5983211A | Search similar patents

Data storage device and method for determining the dependency of the risk for prostate cancer, device and method for indicating a risk for a disease of an individual

A data storage device comprises a memory in which a collection of prostate cancer screening data is stored. The screening data is obtained from a selection of the general male population without medical pre-selection. A device for indicating a risk for a disease of an individual, comprises an indicator for indicating a determined value for said risk. The indicator comprises a risk scale representing a range of values of said risk, and at least one dialler for entering a value of a diagnostic parameter of an individual. The dialler comprises a parameter scale representing a range of values of said diagnostic parameter. The dialler is movable with respect to said indicator such that when a parameter value on said parameter scale is selected, an associated risk value is indicated on said risk scale according to a predetermined mathematical relationship

Publication number: EP1974312A1 | Search similar patents

Computational medical treatment plan method and system with mass medical analysis


The present disclosure is directed toward global medical data analysis methods, systems, and computer program products for analyzing, classifying, and matching mass amounts of medical information from many sources and across different regions. The global medical data analysis system includes a medical main server that contains an intelligent medical engine, which is communicatively coupled to a central database, a confidential electronic medical records database, and further communicatively coupled through a network to hospitals, clinics, and other medical sources. The intelligent medical engine receives voluminous medical record, potentially from different countries, regions, and continents. Electronic Medical records are sourced from hospitals, clinics, and other medical sources, which are fed into the intelligent medical engine for large-scale analysis and correlation of patients' medical records globally. The analysis starts by degrouping (classifying) medical records into multiple levels of subgroups according to patient clinical parameters, disease templates, treatments and outcomes. When a new patient enters the system, that patient's parameters and disease template are matched against the closest subgroups to suggest treatments with potentially favorable outcomes.

Publication number: US2015161331A1 | Search similar patents

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